Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/80361
Title: Combined optical and acoustic resolution photoacoustic microscopy
Authors: Moothanchery, Mohesh
Pramanik, Manojit
Keywords: Photoacoustic Imaging
Optical resolution photoacoustic microscopy
Issue Date: 2017
Source: Moothanchery, M., & Pramanik, M. (2017). Combined optical and acoustic resolution photoacoustic microscopy. Proceeding of SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 100644P-.
Abstract: Photoacoustic imaging is a fast growing in vivo imaging modality combining the optical absorption contrast and high spatial ultrasonic resolution. Using this technique deeper tissue penetration greater than optical mean free path (~1 mm in skin) is possible. Low resolution with deep penetration depth is possible utilizing acoustic focusing and high resolution with shallow imaging depth can be possible by optical focusing using different photoacoustic microscopy (PAM) systems. Here, we present a combined/switchable optical resolution and acoustic resolution photoacoustic microscopy (OR-AR-PAM) system capable of both high resolution and low resolution deep tissue imaging on the same sample. Lateral resolution of 3.9 μm using optical focusing and lateral resolution of 57 μm using acoustic focusing was successfully demonstrated using the combined system.
URI: https://hdl.handle.net/10356/80361
http://hdl.handle.net/10220/42152
DOI: 10.1117/12.2251258
Rights: © 2017 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Proceeding of SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017 and is made available as an electronic reprint (preprint) with permission of SPIE. The published version is available at: http://dx.doi.org/10.1117/12.2251258. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Conference Papers

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