Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/80527
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dc.contributor.authorMakino, Hiroshien
dc.contributor.authorHwang, Eun Jungen
dc.contributor.authorHedrick, Nathan G.en
dc.contributor.authorKomiyama, Takakien
dc.date.accessioned2017-07-25T01:43:20Zen
dc.date.accessioned2019-12-06T13:51:30Z-
dc.date.available2017-07-25T01:43:20Zen
dc.date.available2019-12-06T13:51:30Z-
dc.date.issued2016en
dc.identifier.citationMakino, H., Hwang, E. J., Hedrick, N. G., & Komiyama, T. (2016). Circuit Mechanisms of Sensorimotor Learning. Neuron, 92(4), 705-721.en
dc.identifier.issn0896-6273en
dc.identifier.urihttps://hdl.handle.net/10356/80527-
dc.description.abstractThe relationship between the brain and the environment is flexible, forming the foundation for our ability to learn. Here we review the current state of our understanding of the modifications in the sensorimotor pathway related to sensorimotor learning. We divide the process into three hierarchical levels with distinct goals: (1) sensory perceptual learning, (2) sensorimotor associative learning, and (3) motor skill learning. Perceptual learning optimizes the representations of important sensory stimuli. Associative learning and the initial phase of motor skill learning are ensured by feedback-based mechanisms that permit trial-and-error learning. The later phase of motor skill learning may primarily involve feedback-independent mechanisms operating under the classic Hebbian rule. With these changes under distinct constraints and mechanisms, sensorimotor learning establishes dedicated circuitry for the reproduction of stereotyped neural activity patterns and behavior.en
dc.language.isoenen
dc.relation.ispartofseriesNeuronen
dc.rights© 2016 Elsevier Inc.en
dc.subjectSensorimotor learningen
dc.subjectNeural circuitsen
dc.titleCircuit Mechanisms of Sensorimotor Learningen
dc.typeJournal Articleen
dc.contributor.schoolLee Kong Chian School of Medicine (LKCMedicine)en
dc.identifier.doi10.1016/j.neuron.2016.10.029en
item.grantfulltextnone-
item.fulltextNo Fulltext-
Appears in Collections:LKCMedicine Journal Articles

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