Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/80639
Title: Tailoring thin films for implant-specific applications
Authors: Steele, Terry W. J.
Loo, Joachim Say Chye
Venkatraman, Subbu S.
Keywords: Gradients
Fluorescein
Issue Date: 2016
Publisher: Woodhead Publishing
Source: Steele, T. W. J., Loo, J. S. C., & Venkatraman, S. S. (2016). Tailoring thin films for implant-specific applications. In H. J. Griesser (Ed.), Thin Film Coatings for Biomaterials and Biomedical Applications (pp. 49-60).
Abstract: Research and development of polyester thin film implants can be tailored for controlled drug release, mechanical properties and surface properties. The high number of parameters often makes the optimization process slow and laborious. By employing high-throughput drug release and gradient-casting techniques, we show how these properties can be rapidly optimized. The employment of these techniques has yielded methods in which drug release can be tailored without the use of additives and how the choice of certain additives can change material properties while negligibly affecting drug release. Alternatively, plasma post-treatment may allow tailoring of thin film material properties though the judicious use of plasmas such as oxygen, argon, or a combination of them.
URI: https://hdl.handle.net/10356/80639
http://hdl.handle.net/10220/42183
ISBN: 978-1-78242-453-6
DOI: 10.1016/B978-1-78242-453-6.00003-1
Rights: © 2016 Elsevier Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication in Thin Film Coatings for Biomaterials and Biomedical Applications, published by Woodhead Publishing on behalf of Elsevier Ltd. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document.  The published version is available at: [http://dx.doi.org/10.1016/B978-1-78242-453-6.00003-1].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MSE Journal Articles

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