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Title: From endosomes to the trans-Golgi network
Authors: Lu, Lei
Hong, Wanjin
Keywords: Retromer
Retrograde membrane trafficking
Trans-Golgi network
Issue Date: 2014
Source: Lu, L., & Hong, W. (2014). From endosomes to the trans-Golgi network. Seminars in Cell & Developmental Biology, 31, 30-39.
Series/Report no.: Seminars in Cell & Developmental Biology
Abstract: The retrograde trafficking from endosomes to the trans-Golgi network (TGN) is one of the major endocytic pathways to divert proteins and lipids away from lysosomal degradation. Retrograde transported cargos enter the TGN via two itineraries from either the early endosome/recycling endosome or the late endosome and involve various machinery components such as retromer, sorting nexins, clathrin, small GTPases, tethering factors and SNAREs. Recently, the pathway has been recognized for its role in signal transduction, physiology and pathogenesis of human diseases.
ISSN: 1084-9521
DOI: 10.1016/j.semcdb.2014.04.024
Schools: School of Biological Sciences 
Rights: © 2014 Elsevier Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication by Seminars in Cell & Developmental Biology, Elsevier Ltd. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SBS Journal Articles

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