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Title: Genetics of Type 2 Diabetes and Clinical Utility
Authors: Dorajoo, Rajkumar
Liu, Jianjun
Boehm, Bernhard Otto
Keywords: Type 2 diabetes
Clinical utility
Issue Date: 2015
Source: Dorajoo, R., Liu, J., & Boehm, B. O. (2015). Genetics of Type 2 Diabetes and Clinical Utility. Genes, 6, 372-384.
Series/Report no.: Genes
Abstract: A large proportion of heritability of type 2 diabetes (T2D) has been attributed to inherent genetics. Recent genetic studies, especially genome-wide association studies (GWAS), have identified a multitude of variants associated with T2D. It is thus reasonable to question if these findings may be utilized in a clinical setting. Here we briefly review the identification of risk loci for T2D and discuss recent efforts and propose future work to utilize these loci in clinical setting—for the identification of individuals who are at particularly high risks of developing T2D and for the stratification of specific health-care approaches for those who would benefit most from such interventions.
ISSN: 2073-4425
DOI: 10.3390/genes6020372
Schools: Lee Kong Chian School of Medicine (LKCMedicine) 
Rights: © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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