Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/81359
Title: | Pulsed laser diode based optoacoustic imaging of biological tissues | Authors: | Upputuri, Paul Kumar Pramanik, Manojit |
Keywords: | Optoacoustic tomography Pulsed laser diode Deep tissue imaging Biological imaging |
Issue Date: | 2015 | Source: | Upputuri, P. K., & Pramanik, M. (2015). Pulsed laser diode based optoacoustic imaging of biological tissues. Biomedical Physics & Engineering Express, 1(4), 045010-. | Series/Report no.: | Biomedical Physics & Engineering Express | Abstract: | Optoacoustic tomography (OAT) is a promising hybrid imaging modality for many biomedical applications. However, the use of Nd:YAG laser as excitation source makes the OAT system expensive, and non-portable. Miniaturization of OAT system is an immediate task to make it a potential tool for both preclinical and clinical studies. In this work, we present an OA system that uses a miniaturized pulsed laser diode which can provide near infrared pulses at ~803 nm. With laser fluence ~0.3 mJ cm−2 on the tissue surface, we achieved 3 cm deep imaging in chicken tissue. The high pulse repetition rate of the diode laser allowed rapid acquisition of OA cross-sectional images with good image quality. The results promise that the proposed system has potential to be used as an alternative to Nd:YAG based OAT systems for biological imaging applications. | URI: | https://hdl.handle.net/10356/81359 http://hdl.handle.net/10220/39212 |
ISSN: | 2057-1976 | DOI: | 10.1088/2057-1976/1/4/045010 | Schools: | School of Chemical and Biomedical Engineering | Rights: | © 2015 IOP Publishing Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication by Biomedical Physics & Engineering Express, IOP Publishing Ltd. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1088/2057-1976/1/4/045010]. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SCBE Journal Articles |
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File | Description | Size | Format | |
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Pulsed Laser Diode Based Optoacoustic Imaging of Biological Tissues.pdf | 1.05 MB | Adobe PDF | View/Open |
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