Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/81405
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dc.contributor.authorYong, Derricken
dc.contributor.authorLee, Elizabethen
dc.contributor.authorYu, Xiaen
dc.contributor.authorChan, Chi Chiuen
dc.date.accessioned2016-06-22T07:32:52Zen
dc.date.accessioned2019-12-06T14:30:15Z-
dc.date.available2016-06-22T07:32:52Zen
dc.date.available2019-12-06T14:30:15Z-
dc.date.issued2016en
dc.identifier.citationYong, D., Lee, E., Yu, X., & Chan, C. C. (2016). Fluorospectroscopy of Dye-Loaded Liposomes in Photonic Crystal Fibers. IEEE Journal of Selected Topics in Quantum Electronics, 22(3), 1-6.en
dc.identifier.issn1077-260Xen
dc.identifier.urihttps://hdl.handle.net/10356/81405-
dc.description.abstractThe immobilization and probing of liposomes within photonic crystal fibers was demonstrated for the first time. A bioactive surface was used to tether the liposomes. This bioactive surface consisted of streptavidin bound to a photochemically functionalized biotin layer. Bound streptavidin, hence, enabled the further binding of biotinylated dye-loaded liposomes. In-fiber fluorescence spectroscopy was used to quantify the streptavidin coverage density. The same method was also used to characterize the surface-tethered liposomes. The further observation of a unique phenomenon-photobleaching dequenching-was used for the first time as an indication of liposomal content retention. This indicated no rupturing of liposomes, highlighting them as bioderived analogues to dye-doped nanoparticles. The demonstrated integration of liposomes with optical waveguides shows potential as a biointegrated photonic device.en
dc.format.extent7 p.en
dc.language.isoenen
dc.relation.ispartofseriesIEEE Journal of Selected Topics in Quantum Electronicsen
dc.rights© 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. The published version is available at: [http://dx.doi.org/10.1109/JSTQE.2015.2479919].en
dc.subjectFluorescenceen
dc.subjectLight emitting diodesen
dc.subjectNanoparticlesen
dc.subjectPhotobleachingen
dc.subjectPhotonic crystal fibersen
dc.subjectSpectroscopyen
dc.subjectSurface treatmenten
dc.titleFluorospectroscopy of Dye-Loaded Liposomes in Photonic Crystal Fibersen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.contributor.organizationA*STAR SIMTechen
dc.identifier.doi10.1109/JSTQE.2015.2479919en
dc.description.versionAccepted versionen
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