Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorYong, Derricken
dc.contributor.authorLee, Elizabethen
dc.contributor.authorYu, Xiaen
dc.contributor.authorChan, Chi Chiuen
dc.identifier.citationYong, D., Lee, E., Yu, X., & Chan, C. C. (2016). Fluorospectroscopy of Dye-Loaded Liposomes in Photonic Crystal Fibers. IEEE Journal of Selected Topics in Quantum Electronics, 22(3), 1-6.en
dc.description.abstractThe immobilization and probing of liposomes within photonic crystal fibers was demonstrated for the first time. A bioactive surface was used to tether the liposomes. This bioactive surface consisted of streptavidin bound to a photochemically functionalized biotin layer. Bound streptavidin, hence, enabled the further binding of biotinylated dye-loaded liposomes. In-fiber fluorescence spectroscopy was used to quantify the streptavidin coverage density. The same method was also used to characterize the surface-tethered liposomes. The further observation of a unique phenomenon-photobleaching dequenching-was used for the first time as an indication of liposomal content retention. This indicated no rupturing of liposomes, highlighting them as bioderived analogues to dye-doped nanoparticles. The demonstrated integration of liposomes with optical waveguides shows potential as a biointegrated photonic device.en
dc.format.extent7 p.en
dc.relation.ispartofseriesIEEE Journal of Selected Topics in Quantum Electronicsen
dc.rights© 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. The published version is available at: [].en
dc.subjectLight emitting diodesen
dc.subjectPhotonic crystal fibersen
dc.subjectSurface treatmenten
dc.titleFluorospectroscopy of Dye-Loaded Liposomes in Photonic Crystal Fibersen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.contributor.organizationA*STAR SIMTechen
dc.description.versionAccepted versionen
item.fulltextWith Fulltext-
Appears in Collections:SCBE Journal Articles
SIMTech Journal Articles
Files in This Item:
File Description SizeFormat 
Fluorospectroscopy of Dye-Loaded Liposomes in Photonic Crystal Fibers.pdf708.64 kBAdobe PDFThumbnail

Citations 50

Updated on Jul 9, 2024

Web of ScienceTM
Citations 50

Updated on Oct 26, 2023

Page view(s) 20

Updated on Jul 17, 2024

Download(s) 20

Updated on Jul 17, 2024

Google ScholarTM




Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.