Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/81570
Title: Contact lens assisted imaging with integrated flexible handheld probe for glaucoma diagnosis
Authors: Hong, Jeesmond Xun Jie
Shinoj, Vengalathunadakal Kuttinarayanan
Murukeshan, Vadakke Matham
Baskaran, Mani
Aung, Tin
Keywords: DRNTU::Engineering::Mechanical engineering
Glaucoma
Iridocorneal Angle Imaging
Issue Date: 2017
Source: Hong, J. X. J., Shinoj, V. K., Murukeshan, V. M., Baskaran, M., & Aung, T. (2017). Contact lens assisted imaging with integrated flexible handheld probe for glaucoma diagnosis. Fifth International Conference on Optical and Photonics Engineering, 10449, 1044908-. doi:10.1117/12.2268984
Conference: Fifth International Conference on Optical and Photonics Engineering
Abstract: Angle closure glaucoma accounts for majority of the bilateral blindness in Asian countries such as Singapore, China, and India. Abnormalities in the optic nerve and aqueous outflow system are the most indicative clinical hallmarks for glaucoma of this clinical subtype. Traditional photographic imaging techniques to assess the drainage angle are contact based, and may expose patients to risk of corneal abrasion and infections. In addition, these procedures require the use of viscous ophthalmic gels as coupling medium to overcome the phenomenon of total internal reflection at the tear-air interface. In this paper, we propose an integrated flexible handheld probe consisting of a micro color CCD video camera and white light LEDs. The handheld probe is able to capture images of the fundus and opposite iridocorneal angle when placed at the central cornea or limbus respectively. Here, we propose the use of hydrogel contact lens as an index matching medium and better protective barrier, as an alternative to conventional ophthalmic gels. The proposed imaging system and methodology has been successfully tested on porcine eye samples, ex vivo. With its high repeatability, reproducibility, and a good safety profile, it is believed that the proposed imaging system and methodology will complement existing imaging modalities in the diagnosis and management of glaucoma.
URI: https://hdl.handle.net/10356/81570
http://hdl.handle.net/10220/47494
DOI: 10.1117/12.2268984
Schools: School of Mechanical and Aerospace Engineering 
Rights: © 2017 Society of Photo-optical Instrumentation Engineers. All rights reserved. This paper was published in Fifth International Conference on Optical and Photonics Engineering and is made available with permission of Society of Photo-optical Instrumentation Engineers.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Conference Papers

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