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Title: Development of Semiconducting Polymer Nanoparticles for Photoacoustic Imaging
Authors: Cui, Dong
Xie, Chen
Pu, Kanyi
Keywords: polymer nanoparticles
photoacoustic imaging
Issue Date: 2017
Source: Cui, D., Xie, C., & Pu, K. (2017). Development of Semiconducting Polymer Nanoparticles for Photoacoustic Imaging. Macromolecular Rapid Communications, 38(12), 1700125-.
Series/Report no.: Macromolecular Rapid Communications
Abstract: Semiconducting polymer nanoparticles (SPNs) have evolved into a new class of photonic materials with great potential for biomedical applications. Depending on the polymer structures, SPNs can be developed into optical agents for fluorescence and chemiluminescence imaging, photosensitizers for photodynamic therapy, and heat converters for photothermal therapy. In this feature article, recent work is summarized on the development of SPNs for in vivo photoacoustic (PA) imaging, a state-of-the-art imaging modality that converts light energy into mechanical acoustic waves to provide deep tissue penetration. The structure–property relationship and doping approaches are discussed to reveal the importance of promoting nonradiative decay in amplifying the PA brightness of SPNs. Moreover, their imaging applications, including lymph node mapping, tumor imaging, and monitoring of pathological indexes, are highlighted. These studies demonstrate that SPNs can serve as versatile PA agents for advanced molecular imaging applications.
ISSN: 1022-1336
DOI: 10.1002/marc.201700125
Schools: School of Chemical and Biomedical Engineering 
Rights: © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the author created version of a work that has been peer reviewed and accepted for publication by Macromolecular Rapid Communications, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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