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Title: International union of basic and clinical pharmacology. C. nomenclature and properties of calcium-activated and sodium-activated potassium channels
Authors: Kaczmarek, Leonard K.
Aldrich, Richard W.
Chandy, Kanianthara George
Grissmer, Stephan
Wei, Aguan D.
Wulff, Heike
Keywords: Ca2+-activated
Na+ and Cl−
Issue Date: 2017
Source: Kaczmarek, L. K., Aldrich, R. W., Chandy, K. G., Grissmer, S., Wei, A. D., & Wulff, H. (2016). International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels. Pharmacological Reviews, 69(1), 1-11. doi:10.1124/pr.116.012864
Series/Report no.: Pharmacological Reviews
Abstract: A subset of potassium channels is regulated primarily by changes in the cytoplasmic concentration of ions, including calcium, sodium, chloride, and protons. The eight members of this subfamily were originally all designated as calcium-activated channels. More recent studies have clarified the gating mechanisms for these channels and have documented that not all members are sensitive to calcium. This article describes the molecular relationships between these channels and provides an introduction to their functional properties. It also introduces a new nomenclature that differentiates between calcium- and sodium-activated potassium channels.
ISSN: 0031-6997
DOI: 10.1124/pr.116.012864
Schools: Lee Kong Chian School of Medicine (LKCMedicine) 
Rights: © 2016 The American Society for Pharmacology and Experimental Therapeutics. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:LKCMedicine Journal Articles

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