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Title: Advances in Neutrophil Testing In Type 2 Diabetes Mellitus
Authors: Tay, Hui Min
Hou, Han Wei
Dalan, Rinkoo
Boehm, Bernhard Otto
Keywords: Neutrophils
Issue Date: 2017
Source: Hou, H. W., Tay, H. M., Dalan, R., & Boehm, B. O. (2017). Advances in Neutrophil Testing In Type 2 Diabetes Mellitus. Current Research in Diabetes & Obesity Journal, 1(5), 555572-.
Series/Report no.: Current Research in Diabetes & Obesity Journal
Abstract: Patients with type 2 diabetes mellitus (T2DM) suffer from impaired glucose metabolism which results in low-grade inflammation and activation of the innate immune system. Neutrophils the key effector cells of the innate immune system and heavily implicated in the pathogenesis of T2DM, are promising cell-based inflammatory biomarkers for immune health profiling, provided that they can be rapidly purified and measured with sufficient precision. In this review, we highlight recent advances in neutrophil isolation and functional assay using microfluidics technologies and the potential of their functional phenotype as a novel biomarker of vascular risk in diabetes.
ISSN: 2476-1435
Rights: This work is licensed under Creative Commons Attribution 4.0 License
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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