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|Title:||Evaluation of a Micro-Optical Coherence Tomography for the Corneal Endothelium in an Animal Model||Authors:||Ang, Marcus
Htoon, Hla M.
Lwin, Nyein Chan
Mehta, Jodhbir S.
|Issue Date:||2016||Source:||Ang, M., Konstantopoulos, A., Goh, G., Htoon, H. M., Seah, X., Lwin, N. C., et al. (2016). Evaluation of a Micro-Optical Coherence Tomography for the Corneal Endothelium in an Animal Model. Scientific Reports, 6, 29769-.||Series/Report no.:||Scientific Reports||Abstract:||Corneal diseases are the second most common cause of vision loss1,2, with over 180 million people worldwide estimated to be suffering from secondary visual impairment1. Corneal transplantation still remains the main method for restoring vision once corneal clarity is affected3. Thus, evaluation and imaging of the cornea is important for early diagnosis, to allow for timely intervention and prevention of permanent corneal damage. Recent developments in surgical techniques have enabled surgeons to perform selective replacement of the diseased layer of the cornea – which may lead to improved corneal graft survival and surgical outcomes3. In particular, selective replacement of both the endothelial layer4, and the stromal layer5, may confer advantages such as tectonic stability or a rapid visual recovery, compared to replacing the entire cornea during transplantation. Thus, the role of imaging to delineate corneal layers is becoming increasingly important in the pre-operative, intra-operative and post-operative assessment of patients requiring corneal transplantation.||URI:||https://hdl.handle.net/10356/83117
|ISSN:||2045-2322||DOI:||10.1038/srep29769||Rights:||This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/||Fulltext Permission:||open||Fulltext Availability:||With Fulltext|
|Appears in Collections:||EEE Journal Articles|
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