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Title: Evaluation of a Micro-Optical Coherence Tomography for the Corneal Endothelium in an Animal Model
Authors: Ang, Marcus
Konstantopoulos, Aris
Goh, Gwendoline
Htoon, Hla M.
Seah, Xinyi
Lwin, Nyein Chan
Liu, Xinyu
Chen, Si
Liu, Linbo
Mehta, Jodhbir S.
Keywords: Micro-Optical
Corneal Endothelium
Issue Date: 2016
Source: Ang, M., Konstantopoulos, A., Goh, G., Htoon, H. M., Seah, X., Lwin, N. C., et al. (2016). Evaluation of a Micro-Optical Coherence Tomography for the Corneal Endothelium in an Animal Model. Scientific Reports, 6, 29769-.
Series/Report no.: Scientific Reports
Abstract: Corneal diseases are the second most common cause of vision loss1,2, with over 180 million people worldwide estimated to be suffering from secondary visual impairment1. Corneal transplantation still remains the main method for restoring vision once corneal clarity is affected3. Thus, evaluation and imaging of the cornea is important for early diagnosis, to allow for timely intervention and prevention of permanent corneal damage. Recent developments in surgical techniques have enabled surgeons to perform selective replacement of the diseased layer of the cornea – which may lead to improved corneal graft survival and surgical outcomes3. In particular, selective replacement of both the endothelial layer4, and the stromal layer5, may confer advantages such as tectonic stability or a rapid visual recovery, compared to replacing the entire cornea during transplantation. Thus, the role of imaging to delineate corneal layers is becoming increasingly important in the pre-operative, intra-operative and post-operative assessment of patients requiring corneal transplantation.
ISSN: 2045-2322
DOI: 10.1038/srep29769
Rights: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit
Fulltext Permission: open
Fulltext Availability: With Fulltext
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