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dc.contributor.authorXue, Pengen
dc.contributor.authorBao, Jingnanen
dc.contributor.authorWu, Yafengen
dc.contributor.authorZhang, Yileien
dc.contributor.authorKang, Yuejunen
dc.identifier.citationXue, P., Bao, J., Wu, Y., Zhang, Y., & Kang, Y. (2017). Porous Prussian Blue Nanocubes as Photothermal Ablation Agents for Efficient Cancer Therapy. Journal of Nanoscience and Nanotechnology, 17(1), 168-174. doi:10.1166/jnn.2017.12408en
dc.description.abstractNanomaterial-based photothermal agents have attracted great attention as near-infrared laserdriven ablation agents for tumor therapy. In this work, Prussian blue nanocubes with porous interior were synthesized via controlled chemical etching method and successfully applied for efficient photothermal ablation of tumor cells in vitro. Monodispersed porous Prussian blue nanocubes (115.4±4.7 nm) were produced through a controlled self-etching reaction in the presence of polyvinylpyrrolidone (PVP). Owing to the strong absorbance in near infrared (NIR) region, the resulted porous Prussian blue nanocubes could lead to more than 80% death of Hela cells after being treated with nanocubes of concentration as low as 100 μg mL−1. Compared to the traditional solid Prussian blue nanoparticles, these porous nanocubes can provide extra space for encapsulating anti-cancer drugs in their porous interior. It is anticipated that these porous Prussian blue nanocubes can be applied as an enabling platform to develop the next generation of multifunctional drug carrier for cancer treatments.en
dc.relation.ispartofseriesJournal of Nanoscience and Nanotechnologyen
dc.rights© 2017 American Scientific Publishers . All rights reserved.en
dc.subjectEngineering::Chemical engineeringen
dc.subjectPhotothermal Therapyen
dc.subjectPorous Nanocubesen
dc.titlePorous prussian blue nanocubes as photothermal ablation agents for efficient cancer therapyen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.contributor.schoolSchool of Mechanical and Aerospace Engineeringen
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