Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/83179
Full metadata record
DC FieldValueLanguage
dc.contributor.authorDegirmenci, Ufuken
dc.contributor.authorLei, Sunen
dc.date.accessioned2017-05-24T02:02:49Zen
dc.date.accessioned2019-12-06T15:13:27Z-
dc.date.available2017-05-24T02:02:49Zen
dc.date.available2019-12-06T15:13:27Z-
dc.date.issued2016en
dc.identifier.citationDegirmenci, U.,& Lei, S. (2016). Role of lncRNAs in Cellular Aging. Frontiers in Endocrinology, 7.en
dc.identifier.issn1664-2392en
dc.identifier.urihttps://hdl.handle.net/10356/83179-
dc.description.abstractAging is a universal, intrinsic, and time-dependent biological decay that is linked to intricate cellular processes including cellular senescence, telomere shortening, stem cell exhaustion, mitochondrial dysfunction, and deregulated metabolism. Cellular senescence is accepted as one of the core processes of aging at the organism level. Understanding the molecular mechanism underlying senescence could facilitate the development of potential therapeutics for aging and age-related diseases. Recently, the discovery of long non-coding RNAs (lncRNA) provided insights into a novel regulatory layer that can intervene with cellular senescence. Increasing evidence indicates that targeting lncRNAs may impact on senescence pathways. In this review, we will focus on lncRNAs involved in mechanistic pathways governing cellular senescence.en
dc.description.sponsorshipNMRC (Natl Medical Research Council, S’pore)en
dc.format.extent10 p.en
dc.language.isoenen
dc.relation.ispartofseriesFrontiers in Endocrinologyen
dc.rights© 2016 Degirmenci and Lei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.en
dc.subjectSenescenceen
dc.subjectAgingen
dc.subjectlncRNAen
dc.titleRole of lncRNAs in Cellular Agingen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.identifier.doi10.3389/fendo.2016.00151en
dc.description.versionPublished versionen
item.grantfulltextopen-
item.fulltextWith Fulltext-
Appears in Collections:SCBE Journal Articles
Files in This Item:
File Description SizeFormat 
art%253A10.1186%252Fs13041-016-0272-9.pdf2.72 MBAdobe PDFThumbnail
View/Open

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.