Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/83280
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dc.contributor.authorUpputuri, Paul Kumaren
dc.contributor.authorPramanik, Manojiten
dc.date.accessioned2019-07-03T08:48:30Zen
dc.date.accessioned2019-12-06T15:19:05Z-
dc.date.available2019-07-03T08:48:30Zen
dc.date.available2019-12-06T15:19:05Z-
dc.date.copyright2019en
dc.date.issued2019en
dc.identifier.citationUpputuri, P. K., & Pramanik, M. (2019). Photoacoustic imaging in the second near-infrared window : a review. Journal of Biomedical Optics, 24(04), 1-. doi:10.1117/1.JBO.24.4.040901en
dc.identifier.issn1083-3668en
dc.identifier.urihttps://hdl.handle.net/10356/83280-
dc.description.abstractPhotoacoustic (PA) imaging is an emerging medical imaging modality that combines optical excitation and ultrasound detection. Because ultrasound scatters much less than light in biological tissues, PA generates high-resolution images at centimeters depth. In recent years, wavelengths in the second near-infrared (NIR-II) window (1000 to 1700 nm) have been increasingly explored due to its potential for preclinical and clinical applications. In contrast to the conventional PA imaging in the visible (400 to 700 nm) and the first NIR-I (700 to 1000 nm) window, PA imaging in the NIR-II window offers numerous advantages, including high spatial resolution, deeper penetration depth, reduced optical absorption, and tissue scattering. Moreover, the second window allows a fivefold higher light excitation energy density compared to the visible window for enhancing the imaging depth significantly. We highlight the importance of the second window for PA imaging and discuss the various NIR-II PA imaging systems and contrast agents with strong absorption in the NIR-II spectral region. Numerous applications of NIR-II PA imaging, including whole-body animal imaging and human imaging, are also discussed.en
dc.description.sponsorshipNMRC (Natl Medical Research Council, S’pore)en
dc.format.extent21 p.en
dc.language.isoenen
dc.relation.ispartofseriesJournal of Biomedical Opticsen
dc.rights© 2019 The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.en
dc.subjectPhotoacoustic Imagingen
dc.subjectSecond Near Infra-red Windowen
dc.subjectEngineering::Chemical engineeringen
dc.titlePhotoacoustic imaging in the second near-infrared window : a reviewen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.identifier.doi10.1117/1.JBO.24.4.040901en
dc.description.versionPublished versionen
dc.identifier.rims211649en
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