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Title: Phase-domain photoacoustic sensing
Authors: Gao, Fei
Zhang, Ruochong
Feng, Xiaohua
Liu, Siyu
Ding, Ran
Kishor, Rahul
Qiu, Lei
Zheng, Yuanjin
Keywords: Photoacoustic imaging
Optical absorption
Issue Date: 2017
Source: Gao, F., Zhang, R., Feng, X., Liu, S., Ding, R., Kishor, R., et al. (2017). Phase-domain photoacoustic sensing. Applied Physics Letters, 110(3), 033701-.
Series/Report no.: Applied Physics Letters
Abstract: As one of the fastest-growing imaging modalities in recent years, photoacoustic imaging has attracted tremendous research interest for various applications including anatomical, functional, and molecular imaging. The majority of the photoacoustic imaging systems are based on the time-domain pulsed photoacoustic method, which utilizes a pulsed laser source to induce a wideband photoacoustic signal, revealing optical absorption contrast. An alternative way is the frequency-domain photoacoustic method utilizing the chirping modulation of laser intensity to achieve lower system cost. In this paper, we report another way of the photoacoustic method, called phase-domain photoacoustic sensing, which explores the phase difference between two consequent intensity-modulated laser pulse induced photoacoustic measurements to reveal the optical properties. The basic principle is introduced, modeled, and experimentally validated in this paper, which opens another potential pathway to perform photoacoustic sensing and imaging, eliminating acoustic detection variations beyond the conventional time-domain and frequency-domain photoacoustic methods.
ISSN: 0003-6951
DOI: 10.1063/1.4974326
Schools: School of Electrical and Electronic Engineering 
Rights: © 2017 American Institute of Physics (AIP). This paper was published in Applied Physics Letters and is made available as an electronic reprint (preprint) with permission of American Institute of Physics (AIP). The published version is available at: []. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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