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Title: Spatial-scanning hyperspectral imaging probe for bio-imaging applications
Authors: Lim, Hoong-Ta
Murukeshan, Vadakke Matham
Keywords: Medical imaging
Gradient index optics
Endoscopic imaging
Fiber optics imaging
Image sensors
Issue Date: 2016
Source: Lim, H.-T. & Murukeshan, V. M. (2016). Spatial-scanning hyperspectral imaging probe for bio-imaging applications. Review of Scientific Instruments, 87, 033707-.
Series/Report no.: Review of Scientific Instruments
Abstract: The three common methods to perform hyperspectral imaging are the spatial-scanning, spectral-scanning, and snapshot methods. However, only the spectral-scanning and snapshot methods have been configured to a hyperspectral imaging probe as of today. This paper presents a spatial-scanning (pushbroom) hyperspectral imaging probe, which is realized by integrating a pushbroom hyperspectral imager with an imaging probe. The proposed hyperspectral imaging probe can also function as an endoscopic probe by integrating a custom fabricated image fiber bundle unit. The imaging probe is configured by incorporating a gradient-index lens at the end face of an image fiber bundle that consists of about 50 000 individual fiberlets. The necessary simulations, methodology, and detailed instrumentation aspects that are carried out are explained followed by assessing the developed probe’s performance. Resolution test targets such as United States Air Force chart as well as bio-samples such as chicken breast tissue with blood clot are used as test samples for resolution analysis and for performance validation. This system is built on a pushbroom hyperspectral imaging system with a video camera and has the advantage of acquiring information from a large number of spectral bands with selectable region of interest. The advantages of this spatial-scanning hyperspectral imaging probe can be extended to test samples or tissues residing in regions that are difficult to access with potential diagnostic bio-imaging applications.
ISSN: 0034-6748
DOI: 10.1063/1.4943968
Schools: School of Mechanical and Aerospace Engineering 
Rights: © 2016 American Institute of Physics. This paper was published in Review of Scientific Instruments and is made available as an electronic reprint (preprint) with permission of American Institute of Physics. The published version is available at: []. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Journal Articles

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