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Title: Lab-on-chip microfluidic impedance measurement for laminar flow ratio sensing and differential conductivity difference detection
Authors: Kong, Tian Fook
Shen, Xinhui
Yang, Chun
Keywords: Microscale flows
Issue Date: 2017
Source: Kong, T. F., Shen, X., Marcos, & Yang, C. (2017). Lab-on-chip microfluidic impedance measurement for laminar flow ratio sensing and differential conductivity difference detection. Applied Physics Letters, 110(23), 233501-.
Series/Report no.: Applied Physics Letters
Abstract: We present a microfluidic impedance device for achieving both the flow ratio sensing and the conductivity difference detection between sample stream and reference buffer. By using a flow focusing configuration, with the core flow having a higher conductivity sample than the sheath flow streams, the conductance of the device varies linearly with the flow ratio, with R2 > 0.999. On the other hand, by using deionized (DI)-water sheath flow as a reference, we can detect the difference in conductivity between the buffer of core flow and sheath DI-water with a high detection sensitivity of up to 1 nM of sodium chloride solution. Our study provides a promising approach for on-chip flow mixing characterization and bacteria detection.
ISSN: 0003-6951
DOI: 10.1063/1.4984897
DOI (Related Dataset):
Schools: School of Mechanical and Aerospace Engineering 
Organisations: Maritime Institute
Rights: © 2017 American Institute of Physics (AIP). This paper was published in Applied Physics Letters and is made available as an electronic reprint (preprint) with permission of American Institute of Physics (AIP). The published version is available at: []. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Journal Articles

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