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Title: Thiophene-derived polymer dots for imaging endocytic compartments in live cells and broad-spectrum bacterial killing
Authors: Prasad, Kenath Priyanka
Than, Aung
Li, Nan
Alam SK, Mahasin
Duan, Hongwei
Pu, Kanyi
Zheng, Xinting
Chen, Peng
Keywords: Polymer dots
Issue Date: 2017
Source: Prasad, K. P., Than, A., Li, N., Alam SK, M., Duan, H., Pu, K., et al. (2017). Thiophene-derived polymer dots for imaging endocytic compartments in live cells and broad-spectrum bacterial killing. Materials Chemistry Frontiers, 1(1), 152-157.
Series/Report no.: Materials Chemistry Frontiers
Abstract: In this work, we present a new type of polymer dot synthesized from bithiophene (pTh-Pdot) via a simple and high yield procedure. Owing to their high brightness, excellent photo-stability, good biocompatibility, and molecular size, pTh-Pdots are promising for bioimaging applications. As a proof-of-concept demonstration, pTh-Pdots are herein employed to track the endocytic pathway in live cells. Furthermore, we show that these polymeric nanoparticles can serve as potent antibacterial agents by making use of their ability to disrupt bacterial membranes and high peroxidase mimicking activity.
DOI: 10.1039/C6QM00065G
Schools: School of Chemical and Biomedical Engineering 
Rights: © 2017 The Author(s). Published by The Royal Society of Chemistry and the Chinese Chemical Society. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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