Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/84613
Title: | Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis | Authors: | Schäfer, Jürgen Griese, Matthias Chandrasekaran, Ravishankar Chotirmall, Sanjay Haresh Hartl, Dominik |
Keywords: | Bronchiectasis Cystic Fibrosis |
Issue Date: | 2018 | Source: | Schäfer, J., Griese, M., Chandrasekaran, R., Chotirmall, S. H., & Hartl, D. (2018). Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis. BMC Pulmonary Medicine, 18(1), 79-. | Series/Report no.: | BMC Pulmonary Medicine | Abstract: | Bronchiectasis is a common feature of severe inherited and acquired pulmonary disease conditions. Among inherited diseases, cystic fibrosis (CF) is the major disorder associated with bronchiectasis, while acquired conditions frequently featuring bronchiectasis include post-infective bronchiectasis and chronic obstructive pulmonary disease (COPD). Mechanistically, bronchiectasis is driven by a complex interplay of inflammation and infection with neutrophilic inflammation playing a predominant role. The clinical characterization and management of bronchiectasis should involve a precise diagnostic workup, tailored therapeutic strategies and pulmonary imaging that has become an essential tool for the diagnosis and follow-up of bronchiectasis. Prospective future studies are required to optimize the diagnostic and therapeutic management of bronchiectasis, particularly in heterogeneous non-CF bronchiectasis populations. | URI: | https://hdl.handle.net/10356/84613 http://hdl.handle.net/10220/45114 |
DOI: | 10.1186/s12890-018-0630-8 | Schools: | Lee Kong Chian School of Medicine (LKCMedicine) | Rights: | © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | LKCMedicine Journal Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis.pdf | 1.53 MB | Adobe PDF | View/Open |
SCOPUSTM
Citations
10
34
Updated on Mar 28, 2024
Web of ScienceTM
Citations
10
30
Updated on Oct 28, 2023
Page view(s) 20
629
Updated on Mar 28, 2024
Download(s) 50
119
Updated on Mar 28, 2024
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.