Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/84749
Title: An aPPARent functional consequence in skeletal muscle physiology via peroxisome proliferator-activated receptors
Authors: Liao, Zehuan
Phua, Wendy Wen Ting
Wong, Melissa Xin Yu
Tan, Nguan Soon
Keywords: Peroxisome Proliferator-Activated Receptors
Skeletal Muscle
Issue Date: 2018
Source: Phua, W. W. T., Wong, M. X. Y., Liao, Z., & Tan, N. S. (2018). An aPPARent functional consequence in skeletal muscle physiology via peroxisome proliferator-activated receptors, 19(5), 1425-.
Series/Report no.: International Journal of Molecular Sciences
Abstract: Skeletal muscle comprises 30–40% of the total body mass and plays a central role in energy homeostasis in the body. The deregulation of energy homeostasis is a common underlying characteristic of metabolic syndrome. Over the past decades, peroxisome proliferator-activated receptors (PPARs) have been shown to play critical regulatory roles in skeletal muscle. The three family members of PPAR have overlapping roles that contribute to the myriad of processes in skeletal muscle. This review aims to provide an overview of the functions of different PPAR members in energy homeostasis as well as during skeletal muscle metabolic disorders, with a particular focus on human and relevant mouse model studies.
URI: https://hdl.handle.net/10356/84749
http://hdl.handle.net/10220/45129
ISSN: 1661-6596
DOI: 10.3390/ijms19051425
Rights: © 2018 by The Author(s). Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SBS Journal Articles

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