Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/85465
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dc.contributor.authorWu, Yingjieen
dc.contributor.authorWang, Kaien
dc.contributor.authorHuang, Shuoen
dc.contributor.authorYang, Cangjieen
dc.contributor.authorWang, Mingfengen
dc.date.accessioned2017-09-12T04:23:48Zen
dc.date.accessioned2019-12-06T16:04:12Z-
dc.date.available2017-09-12T04:23:48Zen
dc.date.available2019-12-06T16:04:12Z-
dc.date.issued2017en
dc.identifier.citationWu, Y., Wang, K., Huang, S., Yang, C., & Wang, M. (2017). Near-Infrared Light-Responsive Semiconductor Polymer Composite Hydrogels: Spatial/Temporal-Controlled Release via a Photothermal “Sponge” Effect. ACS Applied Materials & Interfaces, 9(15), 13602-13610.en
dc.identifier.issn1944-8244en
dc.identifier.urihttps://hdl.handle.net/10356/85465-
dc.description.abstractNear-infrared (NIR) light-responsive hydrogels are important for biomedical applications, such as remote-controlled release, but the NIR agents previously used were largely limited to heavy-metal inorganic materials such as gold nanoparticles. In this article, we report a new type of NIR photothermal-responsive hydrogel that can undergo structural changes in response to NIR light for biomedical applications in drug delivery and controlled release. The hydrogels synthesized by integrating a narrow-bandgap semiconductor polymer poly(diketopyrrolopyrrole-alt-3,4-ethylenedioxythiophene) with the polymerization of N-isopropylacrylamide show rapid and reversible mechanical shrinkage upon NIR light irradiation and can serve as carriers for anticancer drug loading and spatial/temporal control of drug release. These stimuli-responsive hydrogels, which can be prepared in different sizes and shapes, integrate photothermal properties and hydrogel characteristics and can provide on-demand, repeated, remote-controlled drug delivery for biomedical applications such as cancer treatment.en
dc.description.sponsorshipMOE (Min. of Education, S’pore)en
dc.format.extent31 p.en
dc.language.isoenen
dc.relation.ispartofseriesACS Applied Materials & Interfacesen
dc.rights© 2017 American Chemical Society. This is the author created version of a work that has been peer reviewed and accepted for publication by ACS Applied Materials & Interfaces, American Chemical Society. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1021/acsami.7b01016].en
dc.subjectControlled Releaseen
dc.subjectDrug Deliveryen
dc.titleNear-Infrared Light-Responsive Semiconductor Polymer Composite Hydrogels: Spatial/Temporal-Controlled Release via a Photothermal “Sponge” Effecten
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.identifier.doi10.1021/acsami.7b01016en
dc.description.versionAccepted versionen
item.fulltextWith Fulltext-
item.grantfulltextopen-
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