Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/85621
Title: Access to P-Stereogenic Phosphinates via N-Heterocyclic Carbene-Catalyzed Desymmetrization of Bisphenols
Authors: Huang, Zhijian
Huang, Xuan
Li, Baosheng
Mou, Chengli
Yang, Song
Song, Bao-An
Chi, Yonggui Robin
Keywords: Bisphenols
Phosphinates
Issue Date: 2016
Source: Huang, Z., Huang, X., Li, B., Mou, C., Yang, S., Song, B.-A., et al. (2016). Access to P-Stereogenic Phosphinates via N-Heterocyclic Carbene-Catalyzed Desymmetrization of Bisphenols. Journal of the American Chemical Society, 138(24), 7524-7527.
Series/Report no.: Journal of the American Chemical Society
Abstract: A carbene-catalyzed desymmetrization of prochiral bisphenol compounds bearing remote P-stereogenic centers is disclosed. The catalytic reactions can be performed on gram scales with 1 mol % N-heterocyclic carbene (NHC) catalyst, providing efficient access to enantiomerically enriched P-stereogenic phosphinates. The chiral phosphinates prepared with our method can find widespread applications as asymmetric organic catalysts and ligands.
URI: https://hdl.handle.net/10356/85621
http://hdl.handle.net/10220/43779
ISSN: 0002-7863
DOI: 10.1021/jacs.6b04624
Rights: © 2016 American Chemical Society
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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