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Title: | Viral and antibody kinetics, and mosquito infectivity of an imported case of Zika fever due to Asian genotype (American strain) in Singapore | Authors: | Tan, Cheong Huat Tan, Li Kiang Hapuarachchi, Hapuarachchige Chanditha Lai, Yee Ling Wong, Pei Sze Jeslyn Mak, Keng Wai Yap, Grace Wong, Wing Yan Leo, Yee Sin Wong, Mei Chun Ng, Lee Ching |
Keywords: | Zika Virus Antibody |
Issue Date: | 2018 | Source: | Tan, C. H., Tan, L. K., Hapuarachchi, H. C., Lai, Y. L., Wong, P. S. J., Yap, G., et al. (2018). Viral and antibody kinetics, and mosquito infectivity of an imported case of Zika fever due to Asian genotype (American strain) in Singapore. Viruses, 10(1), 44-. | Series/Report no.: | Viruses | Abstract: | We report a case of a Singaporean who acquired Zika virus (ZIKV) during a visit to Cuba. The infection was confirmed using molecular and serological methods. This report highlights potential drawbacks of using IgG serology for diagnosis of flavivirus infections in endemic regions. The low viremia detected during the early phase of this case resulted in low mosquito infectivity rates, suggesting the possibility of ZIKV transmission prior to clinical onset. The report also emphasizes the challenges of public health interventions for Zika fever and the importance of sustaining a low vector population to reduce the risk of arbovirus transmission in vulnerable regions. We report a case of a Singaporean who acquired Zika virus (ZIKV) during a visit to Cuba. The infection was confirmed using molecular and serological methods. This report highlights potential drawbacks of using IgG serology for diagnosis of flavivirus infections in endemic regions. The low viremia detected during the early phase of this case resulted in low mosquito infectivity rates, suggesting the possibility of ZIKV transmission prior to clinical onset. The report also emphasizes the challenges of public health interventions for Zika fever and the importance of sustaining a low vector population to reduce the risk of arbovirus transmission in vulnerable regions. |
URI: | https://hdl.handle.net/10356/86306 http://hdl.handle.net/10220/45231 |
ISSN: | 1999-4915 | DOI: | 10.3390/v10010044 | Schools: | School of Biological Sciences | Rights: | © 2018 by The Author(s). Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SBS Journal Articles |
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Viral and Antibody Kinetics, and Mosquito Infectivity of an Imported Case of Zika Fever Due to Asian Genotype (American Strain) in Singapore.pdf | 3.61 MB | Adobe PDF | View/Open |
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