Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/86900
Title: Dendritic Architecture of Principal Basolateral Amygdala Neurons Changes Congruently with Endocrine Response to Stress
Authors: Yee, Poh Soh
Mitra, Rupshi
Hegde, Akshaya
Keywords: Anxiety
Corticosterone
Issue Date: 2017
Source: Hegde, A., Yee, P. S., & Mitra, R. (2017). Dendritic Architecture of Principal Basolateral Amygdala Neurons Changes Congruently with Endocrine Response to Stress. International Journal of Environmental Research and Public Health, 14(7), 779-.
Series/Report no.: International Journal of Environmental Research and Public Health
Abstract: Animals cope with changing environments through changes in behavior. Such plasticity is, however, marked by substantial inter-individual variability. Neuroendocrine reactivity to challenging environments can be an important predictor of resilience. Both basolateral amygdala (BLA) neurons and adrenal glucocorticoid signaling are integral parts of the stress neuroendocrine response. In this report, we test if individual variation in hormonal response to stress is associated with individual variation in the dendritic complexity of BLA neurons. We report a positive correlation between inter-individual variability in glucocorticoid response and neuronal plasticity in the BLA subsequent to a stressor. This suggests that stressful experiences in the past act as significant sculptors of BLA neuronal plasticity and congruent neuroendocrine response.
URI: https://hdl.handle.net/10356/86900
http://hdl.handle.net/10220/44267
ISSN: 1661-7827
DOI: 10.3390/ijerph14070779
Rights: © 2017 by The Author(s). Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SBS Journal Articles

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