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Title: Depth-of-focus extension in optical coherence tomography via multiple aperture synthesis
Authors: Ge, Xin
Wang, Xianghong
Bo, En
Luo, Yuemei
Chen, Si
Liu, Xinyu
Wang, Nanshuo
Chen, Shufen
Chen, Shi
Li, Jinhan
Liu, Linbo
Keywords: Medical Optics Instrumentation
Optical Coherence Tomography
Issue Date: 2017
Source: Bo, E., Luo, Y., Chen, S., Liu, X., Wang, N., Ge, X., et al. (2017). Depth-of-focus extension in optical coherence tomography via multiple aperture synthesis. Optica, 4(7), 701-706.
Series/Report no.: Optica
Abstract: In this paper, we report what we believe is a novel technique to overcome the depth-of-focus (DOF) limitation in optical coherence tomography (OCT). Using confocal optics on a sample arm, we scanned the illumination beam across the under-filled objective lens pupil plane by steering the beam at the pinhole using a microcylindrical lens. The detected interferometric signals from multiple distinctive apertures were digitally refocused, which is analogous to synthetic aperture radar (SAR). Using numerical simulations and imaging experiments, we verified that this technique can maintain a diffraction-limited transverse resolution along a DOF that is ∼10∼10 times larger than the confocal parameter. The ability to extend the DOF without signal loss and sidelobe artifacts may ultimately overcome the DOF limitation in high-resolution OCT.
DOI: 10.1364/OPTICA.4.000701
Rights: ©2017 Optical Society of America (OSA). This paper was published in Biomedical Optics Express and is made available as an electronic reprint (preprint) with permission of Optical Society of America (OSA). The published version is available at: []. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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