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dc.contributor.authorGe, Xinen
dc.contributor.authorWang, Xianghongen
dc.contributor.authorBo, Enen
dc.contributor.authorLuo, Yuemeien
dc.contributor.authorChen, Sien
dc.contributor.authorLiu, Xinyuen
dc.contributor.authorWang, Nanshuoen
dc.contributor.authorChen, Shufenen
dc.contributor.authorChen, Shien
dc.contributor.authorLi, Jinhanen
dc.contributor.authorLiu, Linboen
dc.identifier.citationBo, E., Luo, Y., Chen, S., Liu, X., Wang, N., Ge, X., et al. (2017). Depth-of-focus extension in optical coherence tomography via multiple aperture synthesis. Optica, 4(7), 701-706.en
dc.description.abstractIn this paper, we report what we believe is a novel technique to overcome the depth-of-focus (DOF) limitation in optical coherence tomography (OCT). Using confocal optics on a sample arm, we scanned the illumination beam across the under-filled objective lens pupil plane by steering the beam at the pinhole using a microcylindrical lens. The detected interferometric signals from multiple distinctive apertures were digitally refocused, which is analogous to synthetic aperture radar (SAR). Using numerical simulations and imaging experiments, we verified that this technique can maintain a diffraction-limited transverse resolution along a DOF that is ∼10∼10 times larger than the confocal parameter. The ability to extend the DOF without signal loss and sidelobe artifacts may ultimately overcome the DOF limitation in high-resolution OCT.en
dc.description.sponsorshipNRF (Natl Research Foundation, S’pore)en
dc.description.sponsorshipMOE (Min. of Education, S’pore)en
dc.description.sponsorshipNMRC (Natl Medical Research Council, S’pore)en
dc.format.extent6 p.en
dc.rights©2017 Optical Society of America (OSA). This paper was published in Biomedical Optics Express and is made available as an electronic reprint (preprint) with permission of Optical Society of America (OSA). The published version is available at: []. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.en
dc.subjectMedical Optics Instrumentationen
dc.subjectOptical Coherence Tomographyen
dc.titleDepth-of-focus extension in optical coherence tomography via multiple aperture synthesisen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.contributor.schoolSchool of Electrical and Electronic Engineeringen
dc.description.versionPublished versionen
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