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dc.contributor.authorWang, Haileien
dc.contributor.authorLi, Yien
dc.contributor.authorZhang, Kunen
dc.contributor.authorMa, Yingqunen
dc.contributor.authorLi, Pingen
dc.identifier.citationWang, H., Li, Y., Zhang, K., Ma, Y., & Li, P. (2018). Feasibility and transcriptomic analysis of betalain production by biomembrane surface fermentation of Penicillium novae-zelandiae. AMB Express, 8, 4-.en
dc.description.abstractIn this study, a biomembrane surface fermentation was used to produce red pigments of Penicillium novae-zelandiae, and the significant improvement in pigment production by the addition of 0.4 g/L of tyrosine demonstrated that the red pigments probably contained betalain. Therefore, one red pigment was purified, and identified as 2-decarboxybetanin by high-resolution mass spectrometry (MS) and MS/MS analysis. Transcriptomic analysis revealed the differentially expressed genes and metabolic profile of P. novae-zelandiae in response to different cultivations and exhibited the complete biosynthetic pathway of 2-decarboxybetanin in P. novae-zelandiae. Betalains are important water-soluble nitrogen-containing food coloring agents, obtained mainly from beetroot by chemical extraction. This paper is the first report about the production of betalain by microbial fermentation, and results exhibit the possible use of fungal fermentation in future 2-decarboxybetanin production.en
dc.format.extent10 p.en
dc.relation.ispartofseriesAMB Expressen
dc.rights© The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.en
dc.subjectBiomembrane Surface Cultivationen
dc.titleFeasibility and transcriptomic analysis of betalain production by biomembrane surface fermentation of Penicillium novae-zelandiaeen
dc.typeJournal Articleen
dc.contributor.researchNanyang Environment and Water Research Instituteen
dc.contributor.researchAdvanced Environmental Biotechnology Centre (AEBC)en
dc.description.versionPublished versionen
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