Please use this identifier to cite or link to this item:
Title: Feasibility and transcriptomic analysis of betalain production by biomembrane surface fermentation of Penicillium novae-zelandiae
Authors: Wang, Hailei
Li, Yi
Zhang, Kun
Ma, Yingqun
Li, Ping
Keywords: Betalains
Biomembrane Surface Cultivation
Issue Date: 2018
Source: Wang, H., Li, Y., Zhang, K., Ma, Y., & Li, P. (2018). Feasibility and transcriptomic analysis of betalain production by biomembrane surface fermentation of Penicillium novae-zelandiae. AMB Express, 8, 4-.
Series/Report no.: AMB Express
Abstract: In this study, a biomembrane surface fermentation was used to produce red pigments of Penicillium novae-zelandiae, and the significant improvement in pigment production by the addition of 0.4 g/L of tyrosine demonstrated that the red pigments probably contained betalain. Therefore, one red pigment was purified, and identified as 2-decarboxybetanin by high-resolution mass spectrometry (MS) and MS/MS analysis. Transcriptomic analysis revealed the differentially expressed genes and metabolic profile of P. novae-zelandiae in response to different cultivations and exhibited the complete biosynthetic pathway of 2-decarboxybetanin in P. novae-zelandiae. Betalains are important water-soluble nitrogen-containing food coloring agents, obtained mainly from beetroot by chemical extraction. This paper is the first report about the production of betalain by microbial fermentation, and results exhibit the possible use of fungal fermentation in future 2-decarboxybetanin production.
DOI: 10.1186/s13568-017-0529-4
Rights: © The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:NEWRI Journal Articles

Citations 50

Updated on Sep 4, 2020

Citations 20

Updated on Mar 4, 2021

Page view(s) 20

Updated on Aug 16, 2022

Download(s) 50

Updated on Aug 16, 2022

Google ScholarTM




Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.