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Title: Super-resolution Photoacoustic Microscopy Using Near-field Localization by a Plasmonic Metal Nanoaperture: A Simulation Study
Authors: Park, Byullee
Lee, Hongki
Upputuri, Paul Kumar
Pramanik, Manojit
Kim, Donghyun
Kim, Chulhong
Keywords: Photoacoustic Imaging
Super Resolution Imaging
Issue Date: 2018
Source: Park, B., Lee, H., Upputuri, P. K., Pramanik, M., Kim, D., & Kim, C. (2018). Super-resolution Photoacoustic Microscopy Using Near-field Localization by a Plasmonic Metal Nanoaperture: A Simulation Study. IEEE Journal of Selected Topics in Quantum Electronics, in press.
Series/Report no.: IEEE Journal of Selected Topics in Quantum Electronics
Abstract: Super-resolution microscopy (SRM) is becoming increasingly important to study nanoscale biological structures. Two most widely used devices for SRM are super-resolution fluorescence microscopy (SRFM) and electron microscopy (EM). For biological living samples, however, SRFM is not preferred since it requires exogenous agents and EM is not preferred since vacuum is required for sample preparation. To overcome these limitations of EM and SFRM, we present a simulation study of super-resolution photoacoustic microscopy (SR-PAM). To break the diffraction limit of light, we investigated a sub-10 nm near-field localization by focusing femtosecond laser pulses under the plasmonic nanoaperture. Using this near-field localization as a light source, we numerically studied the feasibility of the SR-PAM with a k-Wave simulation toolbox in MATLAB. In this photoacoustic simulation, we successfully confirmed that the SR-PAM could be a potential method to resolve and image nanoscale structures.
ISSN: 1077-260X
DOI: 10.1109/JSTQE.2018.2796132
Rights: © 2018 Institute of Electrical and Electronics Engineers (IEEE). Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
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