Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/87385
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dc.contributor.authorBasu, Anindyaen
dc.contributor.authorVadanan, Sundaravadanam Vishnuen
dc.contributor.authorLim, Sierinen
dc.date.accessioned2018-07-30T08:12:53Zen
dc.date.accessioned2019-12-06T16:40:43Z-
dc.date.available2018-07-30T08:12:53Zen
dc.date.available2019-12-06T16:40:43Z-
dc.date.issued2018en
dc.identifier.citationBasu, A., Vadanan, S. V., & Lim, S. (2018). A novel platform for evaluating the environmental impacts on bacterial cellulose production. Scientific Reports, 8(1), 5780-.en
dc.identifier.issn2045-2322en
dc.identifier.urihttps://hdl.handle.net/10356/87385-
dc.description.abstractBacterial cellulose (BC) is a biocompatible material with versatile applications. However, its large-scale production is challenged by the limited biological knowledge of the bacteria. The advent of synthetic biology has lead the way to the development of BC producing microbes as a novel chassis. Hence, investigation on optimal growth conditions for BC production and understanding of the fundamental biological processes are imperative. In this study, we report a novel analytical platform that can be used for studying the biology and optimizing growth conditions of cellulose producing bacteria. The platform is based on surface growth pattern of the organism and allows us to confirm that cellulose fibrils produced by the bacteria play a pivotal role towards their chemotaxis. The platform efficiently determines the impacts of different growth conditions on cellulose production and is translatable to static culture conditions. The analytical platform provides a means for fundamental biological studies of bacteria chemotaxis as well as systematic approach towards rational design and development of scalable bioprocessing strategies for industrial production of bacterial cellulose.en
dc.description.sponsorshipNRF (Natl Research Foundation, S’pore)en
dc.format.extent8 p.en
dc.language.isoenen
dc.relation.ispartofseriesScientific Reportsen
dc.rights© 2018 The Author(s) (Nature Publishing Group). This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/en
dc.subjectBacterial Cellulose (BC)en
dc.subjectBiotechnologyen
dc.titleA novel platform for evaluating the environmental impacts on bacterial cellulose productionen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.identifier.doi10.1038/s41598-018-23701-yen
dc.description.versionPublished versionen
item.fulltextWith Fulltext-
item.grantfulltextopen-
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