Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/87445
Title: Hand-held, clinical dual mode ultrasound - photoacoustic imaging of rat urinary bladder and its applications
Authors: Sivasubramanian, Kathyayini
Periyasamy, Vijitha
Dienzo, Rhonnie Austria
Pramanik, Manojit
Keywords: Photoacoustic Cystography
Clearance Study
Issue Date: 2018
Source: Sivasubramanian, K., Periyasamy, V., Dienzo, R. A., & Pramanik, M. (2018). Hand-held, clinical dual mode ultrasound - photoacoustic imaging of rat urinary bladder and its applications. Journal of Biophotonics, in press.
Series/Report no.: Journal of Biophotonics
Abstract: Urinary bladder imaging is critical to diagnose urinary tract disorders, and bladder cancer. There is a great need for safe, non-invasive, and sensitive imaging technique which enables bladder imaging. Photoacoustic imaging is a rapidly growing imaging technique for various biological applications. It can be combined with clinical ultrasound imaging system for hand-held, dual modal ultrasound-photoacoustic real-time imaging. Structural (bladder wall) and functional (accretion of nanoparticles) bladder imaging is shown here with combined ultrasound and photoacoustic imaging in rats. Photoacoustic images of bladder wall is shown using black ink as the contrast agent. Chicken tissues were stacked on the abdomen of the animal to demonstrate the feasibility of photoacoustic imaging till a depth of 2 cm. Also, the feasibility of photoacoustic imaging for a common bladder disorder, vesicoureteral reflux is studied using urinary tract mimicking phantom. It is also shown that a clinical ultrasound system can be used for photoacoustic imaging of non-invasive clearance study of gold nanorods from circulation by monitoring the gradual accumulation of the gold nanorods in the bladder. The time taken for accumulation of nanorods in the bladder can be used as an indicator of the clearance rate of the nanoparticle circulation from the body.
URI: https://hdl.handle.net/10356/87445
http://hdl.handle.net/10220/44467
ISSN: 1864-063X
DOI: 10.1002/jbio.201700317
Schools: School of Chemical and Biomedical Engineering 
Rights: © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the author created version of a work that has been peer reviewed and accepted for publication by Journal of Biophotonics, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1002/jbio.201700317].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

Files in This Item:
File Description SizeFormat 
UB_JBP_rev_final.pdf1.29 MBAdobe PDFThumbnail
View/Open

SCOPUSTM   
Citations 10

52
Updated on Mar 21, 2024

Web of ScienceTM
Citations 10

38
Updated on Oct 29, 2023

Page view(s) 50

466
Updated on Mar 28, 2024

Download(s) 50

171
Updated on Mar 28, 2024

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.