Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/88224
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dc.contributor.authorChan, Hui Lingen
dc.date.accessioned2018-09-05T02:49:11Zen
dc.date.accessioned2019-12-06T16:58:35Z-
dc.date.available2018-09-05T02:49:11Zen
dc.date.available2019-12-06T16:58:35Z-
dc.date.issued2018en
dc.identifier.citationChan, H. L. (2018). Development of small molecule probe for screening of bacterial resistant enzyme and their biomedical applications. Master's thesis, Nanyang Technological University, Singapore.en
dc.identifier.urihttps://hdl.handle.net/10356/88224-
dc.description.abstractThe work in this thesis has been aimed towards development of a small molecular probe for the screening of bacterial resistant enzymes. This thesis is divided into three main parts. Part I incorporates an introduction to gram positive and negative bacteria and its cell structure, β-lactam antibiotics with a brief insight into various core structure that drugs commonly consist of, β-lactamase enzyme mechanisms and the classifications, recent development in the use of small molecular probe for β-lactamase activities monitoring and imaging, as well as the current gaps and proposed work. Part II disclosed on a covalent labelling approach towards imaging AmpC β-lactamase activity on bacteria cell wall. Part III encloses the experimental data and references (Chapter III).en
dc.format.extent68 p.en
dc.language.isoenen
dc.subjectDRNTU::Science::Chemistryen
dc.titleDevelopment of small molecule probe for screening of bacterial resistant enzyme and their biomedical applicationsen
dc.typeThesisen
dc.contributor.supervisorXing Bengangen
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen
dc.description.degreeMaster of Scienceen
dc.identifier.doi10.32657/10220/45819en
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item.grantfulltextopen-
Appears in Collections:SPMS Theses

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