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|Title:||Investigating genes, environments, and their interactions in the service of informing individualized diagnosis and treatment in developmental disabilities||Authors:||Esposito, Gianluca
Borelli, Jessica L.
|Keywords:||Gene x Environment Interactions
Multilevel Approach To Diagnosis And Treatment
|Issue Date:||2018||Source:||Esposito, G., & Borelli, J. L. (2018). Investigating genes, environments, and their interactions in the service of informing individualized diagnosis and treatment in developmental disabilities. Research in Developmental Disabilities, 821-2. doi:10.1016/j.ridd.2018.07.008||Series/Report no.:||Research in Developmental Disabilities||Abstract:||Developmental outcomes are determined by the interactions between myriad factors operating at many different levels (Bronfenbrenner, 1992; Sameroff, 2009). Broadly speaking, these factors may be related to the genetic background of the individual (genotype) as well as from the external world (environment) with which the individual interacts. During development, the interaction between genotype and environment (Genotype × Environment or G × E) is paramount to the ontogeny of the specific phenotype, which is the set of observable characteristics of the individual. Indeed, one way to conceptualize the diverse array of resulting phenotypes is as the result of different genotypes responding to environmental variation in different ways.||URI:||https://hdl.handle.net/10356/88365
|ISSN:||0891-4222||DOI:||10.1016/j.ridd.2018.07.008||Rights:||© 2018 Elsevier. This is the author created version of a work that has been peer reviewed and accepted for publication by Research in Developmental Disabilities, Elsevier. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1016/j.ridd.2018.07.008].||Fulltext Permission:||embargo_20201130||Fulltext Availability:||With Fulltext|
|Appears in Collections:||HSS Journal Articles|
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|2018 RiDD GxE Editorial SC.pdf|
|123.73 kB||Adobe PDF||Under embargo until Nov 30, 2020|
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