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https://hdl.handle.net/10356/88799
Title: | Surface enhanced Raman spectroscopy for malaria diagnosis and intradermal measurements | Authors: | Yuen, Clement Liu, Quan Chen, Keren Ju, Jian Xiong, Aoli Preiser, Peter |
Keywords: | Ramen DRNTU::Science::Biological sciences Surface Enhanced Raman Scattering (SERS) DRNTU::Engineering::Bioengineering |
Issue Date: | 2018 | Source: | Liu, Q., Yuen, C., Chen, K., Ju, J., Xiong, A., & Preiser, P. (2018). Surface enhanced Raman spectroscopy for malaria diagnosis and intradermal measurements. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 10509, 1050902-. doi:10.1117/12.2294539 | Series/Report no.: | Progress in Biomedical Optics and Imaging - Proceedings of SPIE | Conference: | Plasmonics in Biology and Medicine XV | Abstract: | The biomarkers of many diseases such as malaria can be found in intradermal measurements. We will present two surface enhanced Raman spectroscopy (SERS) based methods for the detection of malaria biomarkers in blood, which are comparable to or outperform the standard clinical method. To eliminate the need of drawing blood, we will also report a stainless-steel microneedle based probe for direct intradermal SERS measurements. Moreover, we developed a deformable agarose needle to reduce the risk of sharp injury and cross contamination due to needle reuse. Tests in skin phantoms for glucose measurements demonstrated accuracy comparable to those traditional methods requiring blood drawing. | URI: | https://hdl.handle.net/10356/88799 http://hdl.handle.net/10220/45935 |
DOI: | 10.1117/12.2294539 | Schools: | School of Chemical and Biomedical Engineering School of Biological Sciences |
Rights: | © 2018 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Progress in Biomedical Optics and Imaging - Proceedings of SPIE and is made available as an electronic reprint (preprint) with permission of Society of Photo-optical Instrumentation Engineers (SPIE). The published version is available at: [http://dx.doi.org/10.1117/12.2294539]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SCBE Journal Articles |
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Surface enhanced Raman spectroscopy for malaria diagnosis and intradermal measurements.pdf | 2.19 MB | Adobe PDF | View/Open |
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