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Title: Adaptive coherent photoacoustic sensing
Authors: Gao, Fei
Feng, Xiaohua
Zhang, Ruochong
Liu, Siyu
Zheng, Yuanjin
Keywords: DRNTU::Engineering::Electrical and electronic engineering
Photoacoustic Spectroscopy
Signal To Noise Ratio
Issue Date: 2018
Source: Gao, F., Feng, X., Zhang, R., Liu, S., & Zheng, Y. (2018). Adaptive coherent photoacoustic sensing. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 10494, 104946G-. doi:10.1117/12.2292627
Series/Report no.: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Abstract: Sensitive detection is always crucial to photoacoustic sensing and imaging applications owing to the extremely low conversion efficiency from light to sound. Conventional approach to enhance the signal-to-noise ratio (SNR) of the photoacoustic signal is data averaging, which is quite time-consuming due to multiple data acquisitions for each photoacoustic measurement. Especially for high power pulsed laser source with only 10-20 pulse repetition rate, multiple data averaging will severely degrade the frame rate. In this paper, we present a simple but efficient way, called adaptive coherent photoacoustic (aCPA) sensing to obviously enhance the detected signal SNR with only single laser pulse. More specifically, The proposed aCPA employs an adaptive matched filter to cross-correlate with the raw time-domain PA signal iteratively. The optimum matched filter could be found after several iterations, leading to improved signal SNR. In vivo experimental results show that the proposed aCPA method improved the signal SNR by about 60 dB with single PA measurement. In conventional data averaging, 106 times PA measurements is required to achieve same SNR improvement. In other words, sensing and imaging speed is improved by 106 times in theory. It demonstrates the potential of aCPA to perform highly sensitive photoacoustic sensing and imaging with significantly accelerated speed.
DOI: 10.1117/12.2292627
Rights: © 2018 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Progress in Biomedical Optics and Imaging - Proceedings of SPIE and is made available as an electronic reprint (preprint) with permission of Society of Photo-optical Instrumentation Engineers (SPIE). The published version is available at: []. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:EEE Journal Articles

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