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dc.contributor.authorLee, Hyunen
dc.contributor.authorJang, Tae-Siken
dc.contributor.authorSong, Juhaen
dc.contributor.authorKim, Hyoun-Eeen
dc.contributor.authorJung, Hyun-Doen
dc.identifier.citationLee, H., Jang, T.-S., Song, J., Kim, H.-E., & Jung, H.-D. (2017). The Production of Porous Hydroxyapatite Scaffolds with Graded Porosity by Sequential Freeze-Casting. Materials, 10(4), 367-.en
dc.description.abstractPorous hydroxyapatite (HA) scaffolds with porosity-graded structures were fabricated by sequential freeze-casting. The pore structures, compressive strengths, and biocompatibilities of the fabricated porous HA scaffolds were evaluated. The porosities of the inner and outer layers of the graded HA scaffolds were controlled by adjusting the initial HA contents of the casting slurries. The interface between the dense and porous parts was compact and tightly adherent. The porosity and compressive strengths of the scaffold were controlled by the relative thicknesses of the dense/porous parts. In addition, the porous HA scaffolds showed good biocompatibility in terms of preosteoblast cell attachment and proliferation. The results suggest that porous HA scaffolds with load-bearing parts have potential as bone grafts in hard-tissue engineering.en
dc.description.sponsorshipMOE (Min. of Education, S’pore)en
dc.format.extent12 p.en
dc.rights© 2017 by The Author(s). Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (
dc.subjectPorous Materialsen
dc.titleThe Production of Porous Hydroxyapatite Scaffolds with Graded Porosity by Sequential Freeze-Castingen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.description.versionPublished versionen
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