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Title: Yellow fever cases in Asia: primed for an epidemic
Authors: Lim, Poh Lian
Wasserman, Sean
Tambyah, Paul Anantharajah
Keywords: Aedes Aegypti
Yellow Fever
Issue Date: 2016
Source: Wasserman, S., Tambyah, P. A., & Lim, P. L. (2016). Yellow fever cases in Asia: primed for an epidemic. International Journal of Infectious Diseases, 48, 98-103. doi:10.1016/j.ijid.2016.04.025
Series/Report no.: International Journal of Infectious Diseases
Abstract: There is currently an emerging outbreak of yellow fever in Angola. Cases in infected travellers have been reported in a number of other African countries, as well as in China, representing the first ever documented cases of yellow fever in Asia. There is a large Chinese workforce in Angola, many of whom may be unvaccinated, increasing the risk of ongoing importation of yellow fever into Asia via busy commercial airline routes. Large parts of the region are hyperendemic for the related Flavivirus dengue and are widely infested by Aedes aegypti, the primary mosquito vector of urban yellow fever transmission. The combination of sustained introduction of viraemic travellers, an ecology conducive to local transmission, and an unimmunized population raises the possibility of a yellow fever epidemic in Asia. This represents a major global health threat, particularly in the context of a depleted emergency vaccine stockpile and untested surveillance systems in the region. In this review, the potential for a yellow fever outbreak in Asia is discussed with reference to the ecological and historical forces that have shaped global yellow fever epidemiology. The limitations of surveillance and vector control in the region are highlighted, and priorities for outbreak preparedness and response are suggested.
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2016.04.025
Rights: © 2016 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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