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dc.contributor.authorKerk, Swat Kimen
dc.contributor.authorLai, Hui Yingen
dc.contributor.authorSze, Siu Kwanen
dc.contributor.authorNg, Kee Woeien
dc.contributor.authorSchmidtchen, Arturen
dc.contributor.authorAdav, Sunil Shankaren
dc.identifier.citationKerk, S. K., Lai, H. Y., Sze, S. K., Ng, K. W., Schmidtchen, A., & Adav, S. S. (2018). Bacteria display differential growth and adhesion characteristics on human hair shafts. Frontiers in Microbiology, 9, 2145-. doi:10.3389/fmicb.2018.02145en
dc.description.abstractApart from the skin surface, hair represents a significant tissue component with a capacity of bacterial interactions. New information can be obtained about hair function through the characterization of bacterial adherence, colonization, and responses to hair shafts per se. In this proof-of-principle study, we examine the growth kinetics of Gram-positive Staphylococcus aureus and Staphylococcus epidermidis, and Gram-negative Pseudomonas aeruginosa and Escherichia coli in the presence of human hair shafts. We explore the ability of these bacteria to adhere to and colonize hair shaft surfaces, as well as the resulting impact on the hair’s surface morphology. We show that hair shafts inhibit the growth of Gram-positive S. aureus and S. epidermidis, while the growth kinetics of P. aeruginosa and E. coli remain unaffected. Scanning electron microscope analysis and steeping studies show that P. aeruginosa and E. coli to adhere to and colonize on human hair shafts without significantly affecting the hair shaft’s surface morphology. P. aeruginosa produced a substantial amount of biofilm on the hair shaft surfaces, while E. coli specifically inhabited the edges of the cuticle scales. Taken together, our results demonstrate differences in bacterial responses to human hair shafts, which may provide novel insights into hair and scalp health.en
dc.description.sponsorshipMOE (Min. of Education, S’pore)en
dc.format.extent9 p.en
dc.relation.ispartofseriesFrontiers in Microbiologyen
dc.rights© 2018 Kerk, Lai, Sze, Ng, Schmidtchen and Adav. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.en
dc.subjectDRNTU::Science::Biological sciencesen
dc.subjectHair Shaften
dc.subjectS. Aureusen
dc.titleBacteria display differential growth and adhesion characteristics on human hair shaftsen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Materials Science and Engineeringen
dc.contributor.schoolSchool of Biological Sciencesen
dc.contributor.schoolInterdisciplinary Graduate School (IGS)en
dc.contributor.schoolLee Kong Chian School of Medicine (LKCMedicine)en
dc.contributor.researchNanyang Environment and Water Research Instituteen
dc.description.versionPublished versionen
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