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Title: High-speed, low-cost, pulsed laser diode based second generation desktop photoacoustic tomography system
Authors: Kalva, Sandeep Kumar
Upputuri, Paul Kumar
Pramanik, Manojit
Keywords: Photoacoustic Imaging
Low-cost Pulsed Laser Diodes
DRNTU::Science::Medicine::Biomedical engineering
Issue Date: 2019
Source: Kalva, S. K., Upputuri, P. K., & Pramanik, M. (2019). High-speed, low-cost, pulsed laser diode based second generation desktop photoacoustic tomography system. Optics Letters, 44(1), 81-84. doi:10.1364/OL.44.000081
Series/Report no.: Optics Letters
Abstract: Bulky, expensive Nd:YAG lasers are used in conventional photoacoustic tomography (PAT) systems making them difficult to translate into clinics. Moreover, real-time imaging is not feasible when single-element ultrasound transducer is used with these low pulse repetition rate lasers (10-100 Hz). Low-cost pulsed laser diodes (PLD) can be used instead for photoacoustic imaging due to their high pulse repetition rates and compact size. Together with acoustic reflector based multiple single element ultrasound transducers portable desktop PAT system was developed. This second generation pulsed laser diode based photoacoustic tomography (PLD-PAT-G2) achieved 0.5 s cross-sectional imaging time with a high spatial resolution of ~165 m and an imaging depth of 3 cm. The performance of this system was characterized using phantom and in vivo studies. Dynamic in vivo imaging was also demonstrated by monitoring the fast uptake and clearance of indocyanine green in small animal (rat) brain vasculature.
ISSN: 0146-9592
DOI: 10.1364/OL.44.000081
Rights: © 2019 Optical Society of America (OSA). This is the author created version of a work that has been peer reviewed and accepted for publication by Optics Letters, Optical Society of America (OSA). It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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