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Title: Multifunctional hydrogel nano-probes for atomic force microscopy
Authors: Lee, Jae Seol
Song, Jungki
Kim, Seong Oh
Kim, Seokbeom
Lee, Wooju
Jackman, Joshua A.
Kim, Dongchoul
Cho, Nam-Joon
Lee, Jungchul
Keywords: DRNTU::Engineering::Materials
Atomic Force Microscopy
Gels And Hydrogels
Issue Date: 2016
Source: Lee, J. S., Song, J., Kim, S. O., Kim, S., Lee, W., Jackman, J. A., . . . Lee, J. (2016). Multifunctional hydrogel nano-probes for atomic force microscopy. Nature Communications, 7, 11566-. doi:10.1038/ncomms11566
Series/Report no.: Nature Communications
Abstract: Since the invention of the atomic force microscope (AFM) three decades ago, there have been numerous advances in its measurement capabilities. Curiously, throughout these developments, the fundamental nature of the force-sensing probe—the key actuating element—has remained largely unchanged. It is produced by long-established microfabrication etching strategies and typically composed of silicon-based materials. Here, we report a new class of photopolymerizable hydrogel nano-probes that are produced by bottom-up fabrication with compressible replica moulding. The hydrogel probes demonstrate excellent capabilities for AFM imaging and force measurement applications while enabling programmable, multifunctional capabilities based on compositionally adjustable mechanical properties and facile encapsulation of various nanomaterials. Taken together, the simple, fast and affordable manufacturing route and multifunctional capabilities of hydrogel AFM nano-probes highlight the potential of soft matter mechanical transducers in nanotechnology applications. The fabrication scheme can also be readily utilized to prepare hydrogel cantilevers, including in parallel arrays, for nanomechanical sensor devices.
DOI: 10.1038/ncomms11566
Rights: © 2016 The Author(s) (Published by Nature Publishing Group). This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MSE Journal Articles

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