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https://hdl.handle.net/10356/94086| Title: | On DNA modelling : interaction of a double helicoidal structure with viscous bio-fluid | Authors: | Shu, Jian Jun Lim, C. W. |
Keywords: | DRNTU::Engineering::Mechanical engineering::Bio-mechatronics | Issue Date: | 2001 | Source: | Lim, C. W. & Shu, J. J. (2001). On DNA modelling: Interaction of a double helicoidal structure with viscous bio-fluid. Automedica, 20(3-4), 297-312. | Series/Report no.: | Automedica | Abstract: | The paper aims at extending, utilising and generalising research in nonlinear dynamics of (i) spiral/helicoidal structures, and (ii) viscous, low speed fluid to biomechanical DNA fluidstructure interaction. Employing a nonlinear helicoidal model, the energy stored in a distorted Watson-Crick DNA model subjected to viscous, low speed organic fluid loading is formulated. Numerical solutions based on the variational principle are presented for a linearized flow field as examples. Significant dynamical responses such as deformation components and resultants are discussed. A proposal for matching of DNA sequential characteristics with respect to the nonlinear dynamical responses is outlined in order to reveal information regarding DNA sequencing by means of a fluid-structure dynamical approach. | URI: | https://hdl.handle.net/10356/94086 http://hdl.handle.net/10220/7224 |
ISSN: | 0095-0963 | Schools: | School of Mechanical and Aerospace Engineering | Organisations: | City University of Hong Kong | Rights: | © 2001 OPA (Overseas Publishers Association) N.V. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
| Appears in Collections: | MAE Journal Articles |
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