Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/94432
Title: Nanofluidic devices and their applications
Authors: Abgrall, Patrick
Nguyen, Nam-Trung
Keywords: DRNTU::Engineering::Mechanical engineering
Issue Date: 2008
Source: Abgrall, P., & Nguyen, N. T. (2008). Nanofluidic Devices and Their Applications. Analytical Chemistry, 80 (7), 2326-2341.
Series/Report no.: Analytical chemistry
Abstract: Recent developments in micro- and nanotechnologies made possible the fabrication of devices integrating a deterministic network of nanochannels, i.e., with at least one dimension in a range from 1 to 100 nm. The proximity of this dimension and the Debye length, the size of biomolecules such as DNA or proteins, or even the slip length, added to the excellent control on the geometry gives unique features to nanofluidic devices. This new class of devices not only finds applications wherever less well-defined porous media, such as electrophoresis gels, have been traditionally used but also give a new insight into the sieving mechanisms of biomolecules and the fluid flow at the nanoscale. Beyond this, the control on the geometry allows smarter design resulting, among others, in new separation principles by taking advantage of the anisotropy. This perspective gives an overview on the fabrication technologies of nanofluidic devices and their applications. In the first part, the current state of the art of nanofluidic fabrication is presented. The second part first discusses the key transport phenomena in nanochannels. Current applications of nanofluidic devices are next discussed. Finally, future challenges and possible applications are highlighted.
URI: https://hdl.handle.net/10356/94432
http://hdl.handle.net/10220/7836
DOI: 10.1021/ac702296u
Rights: © 2008 American Chemical Society. This is the author created version of a work that has been peer reviewed and accepted for publication by Analytical Chemistry, American Chemical Society. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: DOI: [http://dx.doi.org/10.1021/ac702296u].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Journal Articles

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