Please use this identifier to cite or link to this item:
Title: C–C bond formation via copper-catalyzed conjugate addition reactions to enones in water at room temperature
Authors: Isley, Nicholas A.
Lipshutz, Bruce H.
Huang, Shenlin
Leong, Wendy Wen Yi
Zhong, Guofu
Issue Date: 2012
Source: Lipshutz, B. H., Huang, S., Leong, W. W. Y., Zhong, G., & Isley, N. A. (2012). C–C Bond Formation via Copper-Catalyzed Conjugate Addition Reactions to Enones in Water at Room Temperature. Journal of the American Chemical Society, 134(49), 19985-19988.
Series/Report no.: Journal of the American chemical society
Abstract: Conjugate addition reactions to enones can now be done in water at room temperature with in situ generated organocopper reagents. Mixing an enone, zinc powder, TMEDA, and an alkyl halide in a micellar environemnt containing catalytic amounts of Cu(I), Ag(I), and Au(III) leads to 1,4-adducts in good isolated yields: no organometallic precursor need be formed.
DOI: 10.1021/ja309409e
Rights: © 2012 American Chemical Society.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

Citations 10

Updated on Feb 5, 2023

Web of ScienceTM
Citations 10

Updated on Feb 3, 2023

Page view(s) 50

Updated on Feb 5, 2023

Google ScholarTM




Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.