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Title: Detection of DNA hybridization on chemically modified graphene platforms
Authors: Giovanni, Marcella
Bonanni, Alessandra
Pumera, Martin
Issue Date: 2012
Source: Giovanni, M., Bonanni, A., & Pumera, M. (2012). Detection of DNA hybridization on chemically modified graphene platforms. The Analyst, 137(3), 580-583.
Series/Report no.: Analyst
Abstract: The increasing demand for simple, low-cost, rapid, sensitive and label-free methods for the detection of DNA sequences and the presence of single nucleotide polymorphisms (SNPs) has become an important issue in biomedical research. In this work, we studied the performances of several chemically modified graphene nanomaterials as sensing platforms by using the electrochemical impedance spectroscopy technique for the detection. We employed a hairpin DNA as a highly selective probe for the detection of SNP correlated to Alzheimer's disease. We believe that our findings may present a foundation for further research and development in graphene-based impedimetric biosensing.
ISSN: 0003-2654
DOI: 10.1039/c1an15910k
Rights: © 2012 The Royal Society of Chemistry.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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