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dc.contributor.authorTng, Danny Jian Hangen
dc.contributor.authorSong, Peiyien
dc.contributor.authorHu, Ruien
dc.contributor.authorLin, Guimiaoen
dc.contributor.authorYong, Ken-Tyeen
dc.identifier.citationTng, D. J. H., Song, P., Hu, R., Lin, G., & Yong, K.-T. (2013). A sustainable approach to individualized disease treatment : The engineering of a multiple use MEMS drug delivery device. 2013 IEEE 5th International Nanoelectronics Conference (INEC), 153-156.en
dc.description.abstractIndividualized disease diagnosis and therapy has emerged as a new direction in the research of future medication. Over the past several years, innovative approaches based on microelectromechanical system (MEMS) technology have demonstrated promising potential in individualized therapy. In this contribution, a sustainable approach for the individualized treatment of chronic disease is presented using a compact, implantable and refillable MEMS drug delivery device with an electrolysis based actuator. As a demonstration, we utilized the device for programmable delivery of a chemotherapy drug for the treatment of pancreatic cancer with an in vitro configuration based on cancer cell colonies. After the delivery of drug using the device, the growth of the colonies has been greatly inhibited as compared with the control samples. These results show that our new approach has a great potential for future in vivo studies and opens up promising opportunities for future medication.en
dc.subjectDRNTU::Engineering::Electrical and electronic engineering::Nanoelectronicsen
dc.titleA sustainable approach to individualized disease treatment : The engineering of a multiple use MEMS drug delivery deviceen
dc.typeConference Paperen
dc.contributor.schoolSchool of Electrical and Electronic Engineeringen
dc.contributor.conferenceIEEE International Nanoelectronics Conference (5th : 2013 : Singapore)en
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