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Title: Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs
Authors: An, Jia
Chua, Chee Kai
Yu, Ting
Li, Huaqiong
Tan, Lay Poh
Keywords: DRNTU::Engineering::Materials::Biomaterials
Issue Date: 2013
Source: An, J., Chua, C. K., Yu, T., Li, H., & Tan, L. P. (2013). Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs. Nanomedicine, 8(4), 591-602.
Series/Report no.: Nanomedicine
Abstract: Nanobiomaterials, a field at the interface of biomaterials and nanotechnologies, when applied to tissue engineering applications, are usually perceived to resemble the cell microenvironment components or as a material strategy to instruct cells and alter cell behaviors. Therefore, they provide a clear understanding of the relationship between nanotechnologies and resulting cellular responses. This review will cover recent advances in nanobiomaterial research for applications in tissue engineering. In particular, recent developments in nanofibrous scaffolds, nanobiomaterial composites, hydrogel systems, laser-fabricated nanostructures and cell-based bioprinting methods to produce scaffolds with nanofeatures for tissue engineering are discussed. As in native niches of cells, where nanofeatures are constantly interacting and influencing cellular behavior, new generations of scaffolds will need to have these features to enable more desirable engineered tissues. Moving forward, tissue engineering will also have to address the issues of complexity and organization in tissues and organs.
DOI: 10.2217/nnm.13.46
Fulltext Permission: none
Fulltext Availability: No Fulltext
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