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Title: Cationic peptidopolysaccharides show excellent broad-spectrum antimicrobial activities and high selectivity
Authors: Hammond, Paula T.
Chan-Park, Mary B.
Li, Peng
Rayatpisheh, Shahrzad
Zhou, Chuncai
Ye, Kai
Poon, Yin Fun
Duan, Hongwei
Issue Date: 2012
Source: Li, P., Zhou, C., Rayatpisheh, S., Ye, K., Poon, Y. F., Hammond, P. T., et al. (2012). Cationic Peptidopolysaccharides Show Excellent Broad-Spectrum Antimicrobial Activities and High Selectivity. Advanced Materials, 24(30), 4130-4137.
Series/Report no.: Advanced materials
Abstract: Facilely synthesized cationic peptidopolysaccharides, which have a bacterial peptidoglycan-mimetic structure, show outstanding broad-spectrum activities against clinically significant bacteria and fungi and low mammalian cytotoxicity. Their structural affinity with microbial cell-wall constituents promotes penetration to reach the cytoplasmic membrane resulting in excellent antimicrobial activity and high selectivity.
ISSN: 1521-4095
DOI: 10.1002/adma.201104186
Rights: © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SCBE Journal Articles

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