Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/98325
Title: Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo
Authors: Yan, Hong
Teh, Cathleen
Sreejith, Sivaramapanicker
Zhu, Liangliang
Kwok, Anna
Fang, Weiqin
Ma, Xing
Nguyen, Kim Truc
Korzh, Vladimir
Zhao, Yanli
Keywords: DRNTU::Engineering::Materials
Issue Date: 2012
Source: Yan, H., Teh, C., Sreejith, S., Zhu, L., Kwok, A., Fang, W., et al. (2012). Functional Mesoporous Silica Nanoparticles for Photothermal-Controlled Drug Delivery In Vivo. Angewandte Chemie International Edition, 51(33), 8373-8377.
Series/Report no.: Angewandte chemie international edition
Abstract: Release me! A new class of photothermal-responsive [2]rotaxane-appended mesoporous silica nanoparticles (MSNPs) was developed. Remote-controlled movement of the α-cyclodextrin ring (green) upon trans–cis isomerization of the azobenzene axle (red) enables the loading and release of drugs on demand (see scheme). Curcumin-loaded MSNPs were shown to release curcumin into zebrafish larvae upon treatment with visible light or heat.
URI: https://hdl.handle.net/10356/98325
http://hdl.handle.net/10220/12452
ISSN: 1433-7851
DOI: 10.1002/anie.201203993
Rights: © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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