Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/98472| Title: | Cephalosporin-3′-diazeniumdiolates : targeted NO-donor prodrugs for dispersing bacterial biofilms | Authors: | Rice, Scott A. Kardak, Bharat G. Howlin, Robert P. Webb, Jeremy S. Faust, Saul N. Kelso, Michael J. Barraud, Nicolas Yepuri, Nageshwar Rao Kjelleberg, Staffan |
Issue Date: | 2012 | Source: | Barraud, N., Kardak, B. G., Yepuri, N. R., Howlin, R. P., Webb, J. S., Faust, S. N., et al. (2012). Cephalosporin-3′-diazeniumdiolates : targeted NO-donor prodrugs for dispersing bacterial biofilms. Angewandte Chemie International Edition, 51(36), 9057-9060. | Series/Report no.: | Angewandte chemie international edition | Abstract: | Just say NO to biofilms: NO-donors are used to disperse a bacterial biofilm so that co-administered antibiotics will kill the more susceptible unattached cells. The chemically stable cephalosporin-3′-diazeniumdiolate NO-donor prodrug (see scheme) is activated by bacterial β-lactamases and facilitates this two-step biofilm erradication. | URI: | https://hdl.handle.net/10356/98472 http://hdl.handle.net/10220/12454 |
ISSN: | 1433-7851 | DOI: | 10.1002/anie.201202414 | Rights: | © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
| Appears in Collections: | SCELSE Journal Articles |
SCOPUSTM
Citations
5
142
Updated on Apr 14, 2025
Web of ScienceTM
Citations
5
118
Updated on Oct 26, 2023
Page view(s) 10
972
Updated on May 5, 2025
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.